A new approach prevents liver damage in animal models of Alagille syndrome

Newswise-Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, caused by mutations in a gene JAG1 In most cases. The mutations affect multiple organs including the liver where it often leads to cholestasis, a condition in which the flow of bile from the liver stops or slows, resulting in a buildup of … Read more